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PREMIER publishes its first scientific paper: Development of a generalised physiologically based kinetic (PBK) model for fish

By Jiaqi (Fiona) Wang, PhD researcher in Environmental Science at Radboud University (Nijmegen, The Netherlands) Pharmaceuticals have been detected as emerging pollutants in global water bodies, potentially affecting aquatic organisms such as fish. Physiologically based kinetic (PBK) models can predict the active pharmaceutical ingredients (API) uptake, distribution, metabolism and excretion of fish and estimate API […]

PREMIER partners will present at SETAC Europe: don´t miss out!

The society of Environmental Toxicology and Chemistry (SETAC) celebrates its 32nd European Annual Meeting. This year will take place on the 15-19th May in Copenhagen, Denmark and online. The event is getting closer and the PREMIER partners are preparing to present some of the results produced during the project. A variety of PREMIER partners from […]

Meet our Scientific Advisory Board: Interview with Marlene Ågerstrand

Marlene Ågerstrand is an Assistant Professor at the Department of Environmental Science of Stockholm University.   What is your field of expertise? My research focuses on understanding science-policy interactions in risk assessment and management of chemicals. Aspects of interest include the evaluation and use of data for decision-making, the efficiency of management options, and the […]

Exploring the feasibility of implementing the design of greener Active Pharmaceutical Ingredients by interviewing experts from pharma industry

By Neele Puhlmann, PhD candidate at Leuphana University Lüneburg, Rodrigo Vidaurre from Ecologic Institute and Prof. Klaus Kümmerer from Leuphana University Lüneburg, all WP4 contributors. Drug discovery and development experts of seven major pharmaceutical companies were interviewed by PREMIER members to explore the opportunities of incorporating environmental considerations into the pharmaceutical R&D process. The interviews […]

PREMIER celebrates its 4th General Assembly  

The PREMIER project held its 4th General Assembly Meeting (GAM) in a virtual setting. The event was organised over three afternoon sessions where partners and scientific advisory board members were able to discuss the project achievements and upcoming challenges as well as to make decisions about the compounds selected for testing. The first session, was […]

Prioritization and selection of APIs using a risk-based approach

By Cristiana Cannata, PhD researcher in Environmental Science at Radboud University (Nijmegen, The Netherlands) & contributor of PREMIER WP1.2 There are more than 1500 active pharmaceutical ingredients (APIs) on the European market. Residues of these APIs can eventually reach the environment and given the enormous number of human medicines being used, it is unclear which […]

PREMIER contributes to the protection of soil

By Joan Tell, Director, EHS Risk Assessment at MSD Sunday December 5th is World Soil Day. This year 2021, it is focused on keeping soil alive and to protect soil biodiversity. Soil holds more than 25% of our planet´s biodiversity, from bacteria to slimy earthworms and is part of critical ecosystems processes on which humans […]

Ecotoxicity testing: guidelines and evaluation

By Alice Marshall, PhD researcher in Environmental Toxicology at University of York & contributor of PREMIER WP2.1; and Caroline Moermond, Sr Policy Advisor at the National Institute for Public Health and the Environment (RIVM), lead of PREMIER WP4 and contributor of WP3. With the continuous development of new and existing pharmaceuticals, investigation into the environmental legacy of active pharmaceutical […]

PREMIER Call for Data: data sources for the prioritization of APIs

One of the aims of the PREMIER project is to develop a framework to prioritise the environmental assessment of existing Active Pharmaceutical Ingredients (APIs). The prioritisation of APIs will follow a risk-based approach, where the predicted exposure concentration (PEC) is combined with an effect-based threshold (ETH), often represented by the Predicted No-Effect Concentration (PNEC). We […]