PREMIER | Prioritisation and Risk Evaluation of Medicines in the EnviRonment

The Prioritisation and Risk Evaluation of Medicines in the EnviRonment, PREMIER project, aims to deliver a novel assessment system for characterising the environmental risks of APIs, and which can be used to:

Screen and prioritise legacy APIs for a tailored environmental assessment

Identify potential hazards associated with APIs in development and explore the options to steer the design process in a greener direction

Make relevant environmental data on APIs more visible and accessible to all stakeholders

Partners

Radboud University Nijmegen	NL
University of York	UK
ECT Oekotoxikologie GmbH	DE
Rijksinstituut voor Volksgezondheid en Milieu	NL
Istituto di Ricerche Farmacologiche Mario Negri	IT
Eidgenoessische Anstalt Fuer Wasserversorgung Abwasserreinigung Und Gewässerschutz	CH
Leuphana Universitat Luneburg	DE
University of Exeter	UK
Teamit Research SL	SP
Simomics Limited	UK
ECOLOGIC INSTITUT gemeinnützige GmbH	DE
Fraunhofer Gesellschaft Zur Foerderung der Angewandten Forschung E.V.	DE
Helsingin Yliopisto	FI
Goeteborgs Universitet	SE
AstraZeneca AB	SE
GlaxoSmithKline Research and development Ltd.	UK
F. Hoffmann-La Roche	CH
BAYER AKTIENGESELLSCHAFT	DE
BRISTOL-MYERS SQUIBB COMPANY CORP	US
NOVARTIS Pharma AG	CH
SANOFI-Aventis Recherche & Developpement	FR
Institute de Recherches Internationales SERVIER	FR
Eli Lilly and Company Limited	DE
The European Medicines Agency	NL
Merck Sharp & Dohme Corp	US

Funding

Funding period: 01/09/2020 to 30/08/2026. Years: 6 (2020-26)
EFPIA companies: 10. Academic & SMEs: 15
Total Budget: € 9 Million
IMI contribution: € 4.5 Million (in cash). EFPIA contribution: € 4.5 Million (in kind)
Project Coordinator: Radboud University Nijmegen
Project Leader: AstraZeneca AB

Acknowledgement

“PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 875508. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA”.

About IMI

The Innovative Medicines Initiative is a partnership between the European Union and the European pharmaceutical industry, represented by the European Federation of Pharmaceutical Industries and Associations (EFPIA). It is working to improve health by speeding up the development of the next generation of medicines, particularly in areas where there is an unmet medical or social need. It works by facilitating collaboration between the key players involved in health research, including universities, research centres, the pharmaceutical and other industries, small and medium-sized enterprises (SMEs), patient organisations, and medicines regulators. IMI is the world's biggest public-private partnership (PPP) in the life sciences.